Ep 21. What Exactly are SSRI’s?

We hear medication terms and names thrown around all of the time. By our friends, social media, even doctors will just suggest something but won’t really take the time to explain. My Therapist is Out and Mikey Whited, Pscyh NP (he/they) are here to help make all that medical jargon really clear for you as we dive into SSRI medication today. 

SSRIs have been around for a long-time and are typically used to help reduce depression symptoms. However these Selective Serotonin Reuptake Inhibitors are so much more! Join us as we talk about how they work (and don’t), how you’re brain and gut are utilized while taking SSRIs and all the details in between. 

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Selective serotonin reuptake inhibitors (SSRIs) are a class of medications primarily used in treating various mental health conditions, particularly depression and anxiety disorders. These medications work by targeting the brain's neurotransmitters, specifically serotonin, a chemical messenger that plays a crucial role in regulating mood, emotions, and behavior.

SSRIs function by blocking the reabsorption (reuptake) of serotonin in the brain.

Serotonin is released by nerve cells and travels between these cells to transmit signals. Once the serotonin has delivered its signal, it's normally reabsorbed by the cell that released it. SSRIs intervene in this process by preventing the reabsorption of serotonin, allowing more serotonin to remain available in the brain. This increased concentration of serotonin helps to improve the transmission of messages between nerve cells, thereby enhancing mood regulation.

The most common conditions SSRIs are prescribed for include major depressive disorder, generalized anxiety disorder, panic disorder, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), social anxiety disorder, and certain eating disorders like bulimia nervosa.

Some of the widely known SSRIs include fluoxetine (Prozac), sertraline (Zoloft), citalopram (Celexa), escitalopram (Lexapro), and paroxetine (Paxil). These medications often come in pill or tablet form and are generally taken once a day, usually in the morning.

It's essential to understand that while SSRIs are effective for many individuals, they may not be suitable for everyone, and their effects can vary from person to person. Factors such as individual differences in brain chemistry, genetics, the severity of the condition, and potential side effects play a significant role in how someone responds to SSRIs.

SSRIs typically take several weeks before their full therapeutic effects are felt.

During the initial period of taking SSRIs, some individuals might experience side effects such as nausea, insomnia, dizziness, headaches, or changes in appetite. These side effects often diminish over time as the body adjusts to the medication. However, it's crucial to communicate any side effects to a healthcare provider to determine the best course of action.

One of the critical aspects of using SSRIs is that discontinuing them abruptly can lead to withdrawal symptoms. It's advisable to work closely with a healthcare professional when starting or discontinuing SSRIs to manage the process gradually and minimize any potential withdrawal effects.

SSRIs are not a one-size-fits-all solution,

and they work best as part of a comprehensive treatment plan that may include therapy, lifestyle changes, and other interventions. Combining SSRIs with therapy, such as cognitive-behavioral therapy (CBT), can often enhance treatment outcomes by addressing the underlying issues contributing to the mental health condition.

For many individuals, SSRIs can be a valuable tool in managing symptoms of depression, anxiety, and related mental health disorders. However, it's crucial to approach medication use under the guidance of a healthcare professional who can assess individual needs, monitor progress, and make informed decisions about treatment options.

In summary, SSRIs are a class of medications that help alleviate symptoms of depression, anxiety, and other mental health disorders by increasing the availability of serotonin in the brain. While they are effective for many individuals, their use should be monitored by healthcare professionals, and their effects can vary among different individuals. Incorporating SSRIs into a comprehensive treatment plan that includes therapy and lifestyle changes can often lead to the best outcomes for mental health conditions.

Guest Bio: Mikey Whited, RN, MSN, PMHNP-BC (he/they) is a psychiatric nurse practitioner working in Los Angeles, California. Mikey specializes in queer and trans psychiatric medication and mental health care for adults and older teens. Mikey is passionate about changing the psychiatry paradigm and providing quality medication education and care for clients in a way that will ACTUALLY work to help clients achieve their lifestyle goals.

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Content warning: medical neglect, suicide

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